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Exercise and Arthritis: The MOBILE Study

One in every six Canadians will experience arthritis – nearly six million by 2026. The most common form of arthritis is knee osteoarthritis (OA). Exercise is essential for Canadians who have knee OA. It reduces pain, improves mobility, and reduces the risk for other health problems, such as heart disease. However, we do not know the best amount, type, or intensity of exercise for knee OA.


We have designed three different programs that focus on either (i) strengthening leg muscles, (ii) stretching and relaxation, or (iii) strengthening, stretching and relaxation. We aim to compare the effectiveness of these three programs on clinical outcomes (strength, pain, mobility) and tissue outcomes (muscle, fat, cartilage).


Women with knee OA will be randomly assigned to participate in one of the three programs. For each, we ask our study participants to commit at least 1 hour, 3 times per week, for 12 weeks. All of the programs will be available between 7:00 and 8:30am on Mondays, Tuesdays, Thursdays and Fridays over the summer of 2015.


Measures will be completed before and after the 12-week period. These measures will be collected on the McMaster campus, as well as at St. Joseph’s Healthcare on Charlton Ave in downtown Hamilton. Measures include strength, pain and mobility, as well as magnetic resonance imaging scans of the knee and thigh. The scans will be evaluated for the quality of muscle and knee cartilage.  


By the end of this program, you’ll have an opportunity to:

1)   Learn about your current mobility and knee health;

2)   Engage with a group of other women experiencing chronic knee problems; and importantly,

3)   Learn new skills in managing with chronic knee problems associated with knee OA.

We would love to hear from you! Please contact us at 905-525-9140 ext. 20748 or email us at mobiliz@mcmaster.ca.




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