Stuart M. Phillips Ph.D.
Director of PACE
My research program has, at its centre, the following research question: what factors serve to maintain, increase, or decrease skeletal muscle mass?
In addition, my research does not only address the absolute mass of skeletal muscle, but also its quality as assessed by the quantity of force it can generate, but also by the metabolic activity of various enzymes and energy consuming pathways. In my lab, we use a human model of resistance or aerobic exercise, immobilization, or aging to study the processes that govern: muscle accretion, in the case of resistance exercise; atrophy, in the case of immobilization; and sarcopenia, in the case of aging. In addition, my research group has studied the interaction of feeding different protein composition and varied meal timing on the processes regulating hypertrophy and disuse atrophy. We employ stable isotope tracers of amino acids to metabolically trace the fate of ingested proteins. Muscle biopsies provide us with mechanistic information regarding processes that regulate protein accretion and degradation. We use Western blotting, RT-PCR, histological, and immunohistochemical methods to examine these mechanisms. I am also very interested in conditions in which muscle wasting occurs, particularly in the elderly.
My research activities in the PACE are centred on projects that look at how nutrition and exercise interact to affect strength and muscle mass in older people or in persons with chronic disease such as type 2 diabetes or obesity. For example, one study examines the effects of short-term training among people with pre-diabetes consuming a diet with or without dairy. Another training study involving older adults, has examined the effects of post-workout dairy consumption.
Dr. Phillips' Research
The effects of a combined resistance and high-intensity interval exercise training program with nutritional supplementation, on strength and physical function in older men. Read More
Please find attached a memo from Robert L. Baker, Dean, Faculty of Science, regarding the appointment of a new Director of PACE, Dr. Stuart Phillips. Read More
The following is a brief message from the new Director of PACE, Professor Stuart Phillips Read More
A brief news article on the importance of getting enough protein in your diet. Read More